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Gene Ontology Information

Protein Name Aip1p
Description Actin cortical patch component; interacts with the actin depolymerizing factor cofilin; inhibits elongation of aged ADP-actin filaments decorated with cofilin to maintain a high level of assembly-competent actin species; required to restrict cofilin localization to cortical patches; putative regulator of cytokinesis; contains WD repeats; mutations in human homolog WDR1 are associated with cardiac hypertrophy
GO Terms:
Biological Process		 level 7: negative regulation of cytokinesis external link
level 7: actin filament depolymerization external link
level 8: positive regulation of actin filament depolymerization external link
level 10: barbed-end actin filament capping external link
GO Terms:
Molecular Function		 level 4: actin filament binding external link
level 5: actin binding external link
GO Terms:
Cellular Component		 level 3: cytoplasm external link
level 4: mating projection tip external link
level 4: actin cortical patch external link
level 5: nucleus external link
level 5: cytoskeleton external link
level 6: cortical actin cytoskeleton external link
level 7: actin filament external link
External source Open in SGD external link
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