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Gene Ontology Information

Protein Name Pso2p
Description Nuclease required for DNA single- and double-strand break repair; acts at a post-incision step in repair of breaks that result from interstrand cross-links produced by a variety of mono- and bi-functional psoralen derivatives; induced by UV-irradiation; forms nuclear foci upon DNA replication stress
GO Terms:
Biological Process
level 5: cellular response to DNA damage stimulus external link
level 6: nucleic acid phosphodiester bond hydrolysis external link
level 6: DNA repair external link
level 7: protection from non-homologous end joining at telomere external link
level 7: interstrand cross-link repair external link
level 8: double-strand break repair via nonhomologous end joining external link
GO Terms:
Molecular Function
level 3: hydrolase activity external link
level 5: metal ion binding external link
level 5: DNA binding external link
level 5: nuclease activity external link
level 6: damaged DNA binding external link
level 6: exonuclease activity external link
level 7: zinc ion binding external link
level 7: 5'-3' exonuclease activity external link
level 8: 5'-3' exodeoxyribonuclease activity external link
GO Terms:
Cellular Component
level 5: nucleus external link
level 5: mitochondrial matrix external link
External source Open in SGD external link
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