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Gene Ontology Information
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Protein Name |
Pah1p |
Description |
Mg2+-dependent phosphatidate (PA) phosphatase; dephosphorylates PA to yield diacylglycerol; regulates phospholipid synthesis, nuclear/ER membrane growth, lipid droplet formation, triacylglycerol synthesis, vacuolar homeostasis and cell wall integrity; phosphorylated by Pho85p/Pho80p, Cdc28p/Cyclin B, PKA, PKC, and CKII, regulating activity, localization, and proteosomal degradation; homolog of mammalian lipins 1 and 2; human homologs LPIN1, LPIN2, LPIN3 complement the null |
GO Terms: Biological Process |
level 3: plasmid maintenance level 4: lipid metabolic process level 4: cellular lipid metabolic process level 5: phospholipid biosynthetic process level 6: lipid droplet organization level 6: fatty acid catabolic process level 7: triglyceride biosynthetic process level 7: aerobic respiration level 8: vacuole fusion, non-autophagic |
GO Terms: Molecular Function |
level 3: hydrolase activity level 6: transcription cis-regulatory region binding level 7: phosphatidate phosphatase activity |
GO Terms: Cellular Component |
level 3: extrinsic component of membrane level 3: cytosol level 3: cytoplasm level 3: membrane level 4: vacuole level 4: endoplasmic reticulum level 5: endoplasmic reticulum membrane level 5: lipid droplet level 5: nuclear membrane level 5: nucleus |
External source |
Open in SGD |
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