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Modelling prediction
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[metab] Optimisation
manipulating gene expression
manipulating TF expression
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Cep3p
Description
Essential kinetochore protein; component of the CBF3 complex that binds the CDEIII region of the centromere; contains an N-terminal Zn2Cys6 type zinc finger domain, a C-terminal acidic domain, and a putative coiled coil dimerization domain
GO Terms:
Biological Process
level 5:
mitotic spindle assembly checkpoint signaling
level 7:
regulation of DNA-templated transcription
level 7:
septin ring assembly
level 8:
regulation of transcription by RNA polymerase II
GO Terms:
Molecular Function
level 4:
DNA-binding transcription factor activity, RNA polymerase II-specific
level 5:
metal ion binding
level 5:
DNA binding
level 6:
DNA binding, bending
level 7:
zinc ion binding
level 8:
centromeric DNA binding
GO Terms:
Cellular Component
level 4:
chromosome, centromeric region
level 4:
kinetochore
level 4:
CBF3 complex
level 5:
nucleus
level 5:
chromosome
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