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Gene Ontology Information

Protein Name Gua1p
Description GMP synthase; highly conserved enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation; reduction-of-function mutation gua1-G388D causes changes in cellular guanine nucleotide pools, defects in general protein synthesis, and impaired translation of GCN4 mRNA
GO Terms:
Biological Process
level 7: purine nucleotide biosynthetic process external link
level 7: glutamine metabolic process external link
level 9: GMP biosynthetic process external link
GO Terms:
Molecular Function
level 3: ligase activity external link
level 4: nucleotide binding external link
level 5: GMP synthase activity external link
level 6: GMP synthase (glutamine-hydrolyzing) activity external link
level 6: ATP binding external link
level 6: pyrophosphatase activity external link
GO Terms:
Cellular Component
level 1: cellular_component external link
level 3: cytoplasm external link
level 3: cytosol external link
External source Open in SGD external link
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