S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Apj1p
Description	Hsp40 chaperone with a role in SUMO-mediated protein degradation; works in concert with Hsp70 and Hsp110 (Sse1p) to promote disaggregation of intranuclear protein inclusions; competes with Hsp104 in disaggregation, supporting turnover instead of refolding; member of DnaJ-like family, conserved across eukaryotes; overexpression interferes with propagation of the [Psi+] prion; forms nuclear foci upon DNA replication stress
GO Terms: Biological Process	level 3: protein folding level 3: protein unfolding level 4: protein refolding level 8: protein sumoylation
GO Terms: Molecular Function	level 4: chaperone binding level 4: heat shock protein binding level 4: ATPase activator activity level 4: unfolded protein binding level 5: Hsp70 protein binding level 5: metal ion binding level 7: zinc ion binding
GO Terms: Cellular Component	level 3: nuclear periphery level 3: cytoplasm level 3: cytosol level 4: mitochondrion level 5: nucleus level 5: nuclear inclusion body
External source	Open in SGD