S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Met4p
Description	Leucine-zipper transcriptional activator; responsible for regulation of sulfur amino acid pathway; requires different combinations of auxiliary factors Cbf1p, Met28p, Met31p and Met32p; feedforward loop exists in the regulation of genes controlled by Met4p and Met32p; can be ubiquitinated by ubiquitin ligase SCF-Met30p, is either degraded or maintained in an inactive state; regulates degradation of its own DNA-binding cofactors by targeting them to SCF-Met30p
GO Terms: Biological Process	level 4: response to arsenic-containing substance level 5: cellular amino acid biosynthetic process level 5: sulfur amino acid metabolic process level 6: response to cadmium ion level 7: methionine biosynthetic process level 7: cysteine biosynthetic process level 8: regulation of transcription by RNA polymerase II level 9: positive regulation of transcription by RNA polymerase II
GO Terms: Molecular Function	level 4: transcription coactivator activity level 5: DNA-binding transcription activator activity, RNA polymerase II-specific level 5: DNA binding level 7: RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO Terms: Cellular Component	level 4: Cbf1-Met4-Met28 complex level 5: nucleus
External source	Open in SGD