S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Nma111p
Description	Serine protease and general molecular chaperone; cleaves Roq1p, which modifies the substrate specificity of the Ubr1p Ub-ligase, promoting the stress-induced homeostatically-regulated protein degradation (SHRED) of misfolded and native ER-membrane and cytosolic proteins; chaperone activity involved in the heat stress response; promotes apoptosis through proteolysis of Bir1p; role in lipid homeostasis; mammalian Omi/HtrA2 serine protease family member
GO Terms: Biological Process	level 4: cellular lipid metabolic process level 5: protein catabolic process level 5: cellular response to heat level 5: stress-induced homeostatically regulated protein degradation pathway level 5: proteolysis level 5: apoptotic process level 6: regulation of ubiquitin-protein transferase activity
GO Terms: Molecular Function	level 3: hydrolase activity level 4: peptidase activity level 5: serine-type peptidase activity level 6: serine-type endopeptidase activity
GO Terms: Cellular Component	level 5: nucleus
External source	Open in SGD