S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Srv2p
Description	CAP (cyclase-associated protein); N-terminus binds adenylate cyclase and facilitates activation by RAS; N-terminus forms novel hexameric star-shaped shuriken structures that directly catalyze cofilin-mediated severing of actin filaments; C-terminus binds and recycles cofilin bound, ADP-actin monomers, facilitating regulation of actin dynamics and cell morphogenesis; N- and C-termini can function as physically separate proteins; mCAP1 is the mouse homolog
GO Terms: Biological Process	level 4: actin filament severing level 5: actin filament organization level 6: regulation of adenylate cyclase activity level 6: cytoskeleton organization level 6: positive regulation of mitochondrial fission level 6: Ras protein signal transduction level 7: cAMP-mediated signaling level 7: actin filament depolymerization level 8: regulation of actin filament polymerization level 8: positive regulation of actin filament depolymerization
GO Terms: Molecular Function	level 5: actin binding level 5: adenylate cyclase binding
GO Terms: Cellular Component	level 3: cytoplasm level 4: actin cortical patch level 4: mating projection tip level 5: cytoskeleton
External source	Open in SGD