Yeastract
Please fill in here our
user satisfaction survey
Thank you!
YEASTRACT+ INESC-ID IST IBB
Home > Go Back > View Contact/Credits     Tutorial     Help

 

Gene Ontology Information

Protein Name Lto1p
Description Substrate-specific adaptor protein involved in apo-Rli1p maturation; subunit of the Yae1-Lto1 complex, recruiting apo-Rli1p to the CIA targeting complex, facilitating the insertion of an Fe/S cluster by the Fe-S biosynthetic machinery; deca-GX3 motif crucial for complex formation; essential for aerobic but not anaerobic growth; homolog of human ORAOV1, which is overexpressed in solid tumors; co-expression of ORAOV1 and YAE1 homolog YAE1D1 restores growth and Rli1p maturation after LTO1 depletion
GO Terms:
Biological Process
level 7: protein maturation by [4Fe-4S] cluster transfer external link
GO Terms:
Molecular Function
level 3: protein-macromolecule adaptor activity external link
GO Terms:
Cellular Component
level 3: cytoplasm external link
level 3: Yae1-Lto1 complex external link
level 5: nucleus external link
External source Open in SGD external link
w3c xhtml validator w3c css validator