S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rfa2p
Description	Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination; RPA protects against inappropriate telomere recombination, and upon telomere uncapping, prevents cell proliferation by a checkpoint-independent pathway; in concert with Sgs1p-Top2p-Rmi1p, stimulates DNA catenation/decatenation activity of Top3p; protein abundance increases in response to DNA replication s
GO Terms: Biological Process	level 4: establishment of protein localization level 4: reciprocal meiotic recombination level 6: heteroduplex formation level 6: DNA topological change level 6: DNA repair level 6: DNA recombination level 6: DNA replication level 7: telomere maintenance via recombination level 7: nucleotide-excision repair level 7: mitotic recombination level 7: telomere maintenance via telomere lengthening level 8: double-strand break repair via homologous recombination level 8: DNA unwinding involved in DNA replication level 8: telomere maintenance via telomerase level 8: protein ubiquitination
GO Terms: Molecular Function	level 4: nucleic acid binding level 5: DNA binding level 6: sequence-specific DNA binding level 6: double-stranded DNA binding level 6: single-stranded DNA binding
GO Terms: Cellular Component	level 4: site of double-strand break level 4: chromosome, telomeric region level 4: DNA replication factor A complex level 5: nucleus level 6: condensed nuclear chromosome
External source	Open in SGD