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Gene Ontology Information

Protein Name Atg3p
Description E2-like enzyme; involved in autophagy and cytoplasm-to-vacuole targeting (Cvt) pathway; plays a role in formation of Atg8p-phosphatidylethanolamine conjugates, which are involved in membrane dynamics during autophagy and Cvt; interaction with Atg8p regulated by acetylation by NuA4 histone acetyltransferase Esa1p while attenuation of Atg3 acetylation is mediated by histone deacetylase Rpd3p; Atg12p-Atg5p conjugate enhances E2 activity of Atg3p by rearranging its catalytic site
GO Terms:
Biological Process
level 4: autophagy external link
level 4: cytoplasm to vacuole transport by the Cvt pathway external link
level 5: protein transport external link
level 5: autophagy of nucleus external link
level 5: autophagy of mitochondrion external link
level 6: piecemeal microautophagy of the nucleus external link
level 6: late nucleophagy external link
level 7: C-terminal protein lipidation external link
level 7: autophagosome assembly external link
GO Terms:
Molecular Function
level 4: ubiquitin-like protein transferase activity external link
level 5: Atg8 ligase activity external link
GO Terms:
Cellular Component
level 3: phagophore assembly site external link
level 3: cytoplasm external link
level 3: phagophore external link
level 3: cytosol external link
level 4: cytoplasmic ubiquitin ligase complex external link
External source Open in SGD external link
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