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Gene Ontology Information

Protein Name Bre5p
Description Ubiquitin protease cofactor; forms deubiquitination complex with Ubp3p that coregulates anterograde and retrograde transport between the ER and Golgi compartments, deubiquitinating COPII and COPI vesicle coat constituents, Sec23p and Sec27p; involved along with Ubp3p in the steady-state retention of Golgi membrane proteins, such as glycosyltransferases; null is sensitive to brefeldin A
GO Terms:
Biological Process		 level 5: protein retention in Golgi apparatus external link
level 6: regulation of ER to Golgi vesicle-mediated transport external link
level 6: regulation of retrograde vesicle-mediated transport, Golgi to ER external link
level 7: protein deubiquitination external link
level 7: ribophagy external link
GO Terms:
Molecular Function		 level 5: RNA binding external link
level 6: mRNA binding external link
GO Terms:
Cellular Component		 level 3: Ubp3-Bre5 deubiquitination complex external link
level 3: ribonucleoprotein complex external link
level 3: cytoplasm external link
level 3: cytosol external link
level 5: P-body external link
External source Open in SGD external link
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