S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Sin3p
Description	Component of both the Rpd3S and Rpd3L histone deacetylase complexes; involved in transcriptional repression and activation of diverse processes, including mating-type switching and meiosis; involved in the maintenance of chromosomal integrity
GO Terms: Biological Process	level 3: cell division level 3: cell cycle level 4: negative regulation of transcription involved in meiotic cell cycle level 5: autophagy of nucleus level 5: chromatin organization level 5: regulation of transcription involved in G2/M transition of mitotic cell cycle level 6: positive regulation of transcription from RNA polymerase II promoter in response to heat stress level 6: rDNA chromatin condensation level 7: regulation of DNA-templated transcription level 7: histone deacetylation level 8: double-strand break repair via nonhomologous end joining level 9: positive regulation of transcription by RNA polymerase II level 9: negative regulation of silent mating-type cassette heterochromatin formation level 9: negative regulation of ribosomal DNA heterochromatin formation level 9: negative regulation of transcription by RNA polymerase I level 9: negative regulation of transcription by RNA polymerase II level 9: regulation of DNA-templated DNA replication initiation level 10: transfer RNA gene-mediated silencing
GO Terms: Molecular Function	level 4: transcription corepressor activity level 4: transcription coactivator activity
GO Terms: Cellular Component	level 3: chromatin level 4: histone deacetylase complex level 4: Rpd3L-Expanded complex level 4: Sin3-type complex level 5: nucleus level 5: Rpd3S/Clr6-CII complex level 5: Rpd3L complex
External source	Open in SGD