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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Ntg2p
Description
DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase; involved in base excision repair, localizes to the nucleus; sumoylated; NTG2 has a paralog, NTG1, that arose from the whole genome duplication
GO Terms:
Biological Process
level 2:
metabolic process
level 5:
cellular response to DNA damage stimulus
level 6:
DNA repair
level 6:
base-excision repair, AP site formation
level 7:
base-excision repair
level 8:
nucleotide-excision repair, DNA incision, 5'-to lesion
GO Terms:
Molecular Function
level 2:
catalytic activity
level 3:
hydrolase activity
level 3:
lyase activity
level 4:
iron-sulfur cluster binding
level 4:
hydrolase activity, acting on glycosyl bonds
level 5:
metal ion binding
level 5:
4 iron, 4 sulfur cluster binding
level 5:
class I DNA-(apurinic or apyrimidinic site) endonuclease activity
level 5:
DNA binding
level 5:
DNA-(apurinic or apyrimidinic site) endonuclease activity
level 5:
DNA N-glycosylase activity
level 7:
oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
GO Terms:
Cellular Component
level 4:
mitochondrion
level 5:
nucleus
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