S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Hst1p
Description	NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p complex required for ORC-dependent silencing and meiotic repression; non-essential subunit of the Set3C deacetylase complex; involved in telomere maintenance; HST1 has a paralog, SIR2, that arose from the whole genome duplication
GO Terms: Biological Process	level 4: sporulation resulting in formation of a cellular spore level 5: chromatin organization level 9: negative regulation of mitotic recombination level 10: silent mating-type cassette heterochromatin formation
GO Terms: Molecular Function	level 3: transferase activity level 4: protein lysine deacetylase activity level 5: NAD+ binding level 5: metal ion binding level 6: NAD-dependent histone deacetylase activity level 7: zinc ion binding level 7: NAD-dependent histone deacetylase activity (H4-K16 specific)
GO Terms: Cellular Component	level 4: Set3 complex level 5: nucleus
External source	Open in SGD