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Gene Ontology Information

Protein Name Mhf1p
Description Component of the heterotetrameric MHF histone-fold complex; in humans the MHF complex interacts with both DNA and Mph1p ortholog FANCM, a Fanconi anemia complementation group protein, to stabilize and remodel blocked replication forks and repair damaged DNA; mhf1 srs2 double mutants are MMS hypersensitive; ortholog of human centromere constitutive-associated network (CCAN) subunit CENP-S, also known as MHF1
GO Terms:
Biological Process		 level 5: cellular response to DNA damage stimulus external link
level 5: resolution of meiotic recombination intermediates external link
level 6: DNA repair external link
level 7: replication fork processing external link
GO Terms:
Molecular Function		 level 1: molecular_function external link
level 3: chromatin binding external link
level 5: DNA binding external link
level 5: protein heterodimerization activity external link
GO Terms:
Cellular Component		 level 4: Fanconi anaemia nuclear complex external link
level 4: FANCM-MHF complex external link
External source Open in SGD external link
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