S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rtc1p
Description	Subunit of SEACAT, a subcomplex of the SEA complex; Rtc1p, along with Mtc5p and Sea4p, redundantly inhibit the TORC1 inhibitory role of the Iml1p/SEACIT (Iml1p-Npr2p-Npr3p) subcomplex, a GAP for GTPase Gtr1p (EGOC subunit) in response to amino acid limitation, thereby resulting in activation of TORC1 signaling; SEA is a coatomer-related complex that associates dynamically with the vacuole; has N-terminal WD-40 repeats and a C-terminal RING motif; null suppresses cdc13-1
GO Terms: Biological Process	level 5: protein transport level 6: cellular response to amino acid starvation level 8: positive regulation of TOR signaling level 9: positive regulation of macroautophagy level 9: positive regulation of TORC1 signaling
GO Terms: Molecular Function	level 5: metal ion binding level 7: zinc ion binding
GO Terms: Cellular Component	level 3: membrane level 3: Seh1-associated complex level 3: GATOR2 complex level 3: cytosol level 4: vacuole level 5: vacuolar membrane level 6: fungal-type vacuole level 6: extrinsic component of fungal-type vacuolar membrane
External source	Open in SGD