S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rrp40p
Description	Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; predicted to contain both S1 and KH RNA binding domains; mutations in the human homolog, EXOSC3, cause pontocerebellar hypoplasia with motor neuron degeneration
GO Terms: Biological Process	level 7: rRNA processing level 8: CUT catabolic process level 8: nuclear polyadenylation-dependent mRNA catabolic process level 8: small regulatory ncRNA 3'-end processing level 8: exonucleolytic catabolism of deadenylated mRNA level 9: exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) level 9: nuclear-transcribed mRNA catabolic process, non-stop decay level 9: nonfunctional rRNA decay level 9: nuclear polyadenylation-dependent rRNA catabolic process level 9: nuclear polyadenylation-dependent tRNA catabolic process level 9: U4 snRNA 3'-end processing level 10: nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay level 10: nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' level 10: polyadenylation-dependent snoRNA 3'-end processing
GO Terms: Molecular Function	level 5: RNA binding level 7: manganese ion binding
GO Terms: Cellular Component	level 3: cytoplasm level 4: nuclear exosome (RNase complex) level 4: cytoplasmic exosome (RNase complex) level 4: exosome (RNase complex) level 5: nucleus level 5: nucleolus
External source	Open in SGD