S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Dnl4p
Description	DNA ligase required for nonhomologous end-joining (NHEJ); forms stable heterodimer with required cofactor Lif1p, interacts with Nej1p; involved in meiosis, not essential for vegetative growth; mutations in human ortholog lead to ligase IV syndrome and Dubowitz syndrome
GO Terms: Biological Process	level 3: cell division level 3: cell cycle level 5: cellular response to DNA damage stimulus level 6: DNA replication level 6: DNA repair level 6: nucleotide-excision repair, DNA gap filling level 6: DNA biosynthetic process level 6: DNA recombination level 7: DNA ligation involved in DNA repair level 7: maintenance of rDNA level 8: double-strand break repair via nonhomologous end joining
GO Terms: Molecular Function	level 3: ligase activity level 4: nucleotide binding level 5: DNA binding level 5: DNA ligase activity level 5: metal ion binding level 6: DNA ligase (ATP) activity level 6: ATP binding
GO Terms: Cellular Component	level 4: DNA ligase IV complex level 5: nucleus
External source	Open in SGD