S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Exo1p
Description	5'-3' exonuclease and flap-endonuclease; involved in recombination, double-strand break repair, MMS2 error-free branch of the post replication (PRR) pathway and DNA mismatch repair; role in telomere maintenance; member of the Rad2p nuclease family, with conserved N and I nuclease domains; relative distribution to the nucleus increases upon DNA replication stress; EXO1 has a paralog, DIN7, that arose from the whole genome duplication
GO Terms: Biological Process	level 3: gene conversion at mating-type locus level 4: meiotic DNA double-strand break processing level 5: cellular response to DNA damage stimulus level 6: DNA recombination level 6: nucleic acid phosphodiester bond hydrolysis level 6: telomere maintenance level 6: DNA double-strand break processing level 6: DNA repair level 6: mitotic G2/M transition checkpoint level 7: telomeric 3' overhang formation level 7: mismatch repair
GO Terms: Molecular Function	level 2: catalytic activity level 3: hydrolase activity level 4: hydrolase activity, acting on ester bonds level 5: metal ion binding level 5: DNA binding level 5: nuclease activity level 6: exonuclease activity level 7: 5'-3' exonuclease activity level 8: 5'-flap endonuclease activity level 8: 5'-3' exodeoxyribonuclease activity
GO Terms: Cellular Component	level 3: cytoplasm level 5: nucleus
External source	Open in SGD