S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Whi2p
Description	Negative regulator of TORC1 in response to limiting leucine; suppresses TORC1 activity with binding partners Psr1p/Psr2p, acting in parallel with SEACIT; regulates cell cycle arrest in stationary phase; inhibits Ras-cAMP-PKA regulation of apoptosis during nutrient depletion; required with Psr1p for activation of the general stress response; role in rapamycin-induced mitophagy; localizes to the cell periphery; human tumor suppressor and Whi2-like protein KCTD11 functionally complements the null
GO Terms: Biological Process	level 3: cell cycle level 5: actin filament organization level 5: autophagy of mitochondrion level 6: endocytosis level 6: positive regulation of transcription from RNA polymerase II promoter in response to heat stress level 8: positive regulation of G1 to G0 transition level 9: negative regulation of TORC1 signaling
GO Terms: Molecular Function	level 5: RNA binding level 6: protein phosphatase binding
GO Terms: Cellular Component	level 3: cell periphery level 5: nucleus
External source	Open in SGD