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Gene Ontology Information

Protein Name Tmc1p
Description AN1-type zinc finger protein, effector of proteotoxic stress response; stress-inducible transcriptional target of Rpn4p; induced by nitrogen limitation, weak acid, misfolded proteins; short-lived protein, degraded by proteasome; may protect cells from trivalent metalloid induced proteotoxicity; contains PACE promoter element; ortholog of human AIRAP, which stimulates proteasome activity in response to arsenic; protein abundance increases under DNA replication stress
GO Terms:
Biological Process		 level 5: cellular response to arsenic-containing substance external link
level 6: cellular response to misfolded protein external link
GO Terms:
Molecular Function		 level 5: metal ion binding external link
level 7: zinc ion binding external link
GO Terms:
Cellular Component		 level 3: cytoplasm external link
level 5: nucleus external link
External source Open in SGD external link
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