S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ski7p
Description	GTP-binding protein that couples the Ski complex and exosome; putative pseudo-translational GTPase involved in 3'-to-5' mRNA decay pathway; interacts with both the cytoplasmic exosome and the Ski complex; eRF3-like domain targets nonstop mRNA for degradation; null mutants have a superkiller phenotype; SKI7 has a paralog, HBS1, that arose from the whole genome duplication
GO Terms: Biological Process	level 5: translation level 5: protein catabolic process level 6: translational elongation level 7: regulation of translation level 9: nuclear-transcribed mRNA catabolic process, non-stop decay level 9: nonfunctional rRNA decay level 9: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay level 10: nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay level 10: nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
GO Terms: Molecular Function	level 3: protein-macromolecule adaptor activity level 3: protein-containing complex binding level 4: nucleotide binding level 5: translation elongation factor activity level 6: GTP binding level 8: GTPase activity
GO Terms: Cellular Component	level 3: cytoplasm level 3: cytosol
External source	Open in SGD