S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Dia2p
Description	Origin-binding F-box protein; forms SCF ubiquitin ligase complex with Skp1p and Cdc53p; functions in ubiquitination of silent chromatin structural protein Sir4p; required to target Cdc6p for destruction during G1 phase; required for deactivation of Rad53 checkpoint kinase, completion of DNA replication during recovery from DNA damage, assembly of RSC complex, RSC-mediated transcription regulation, and nucleosome positioning; involved in invasive and pseudohyphal growth
GO Terms: Biological Process	level 3: cell cycle level 6: protein-containing complex disassembly level 7: invasive growth in response to glucose limitation level 7: regulation of DNA replication level 8: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process level 8: subtelomeric heterochromatin formation level 8: ubiquitin-dependent protein catabolic process level 8: protein ubiquitination level 10: silent mating-type cassette heterochromatin formation
GO Terms: Molecular Function	level 5: ubiquitin-protein transferase activity level 8: DNA replication origin binding
GO Terms: Cellular Component	level 4: chromosome, telomeric region level 4: nuclear replication fork level 5: nucleus level 6: SCF ubiquitin ligase complex
External source	Open in SGD