S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rio1p
Description	Serine kinase involved in cell cycle regulation and rDNA integrity; associated with late pre-40S particles via its conserved C-terminal domain; prevents premature use of pre-40S particles in translation; association with pre-40S particles regulated by its catalytic ATPase site and likely occurs after the release of Rio2p from these particles; involved in cell cycle progression and processing of the 20S pre-rRNA into mature 18S rRNA; phosphorylates Rpa43p in anaphase to remove Pol I from rDNA
GO Terms: Biological Process	level 3: cell division level 3: cell cycle level 6: phosphorylation level 6: protein phosphorylation level 6: ribosome biogenesis level 7: maturation of SSU-rRNA level 8: positive regulation of rRNA processing level 8: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) level 8: regulation of exit from mitosis level 9: negative regulation of transcription by RNA polymerase I
GO Terms: Molecular Function	level 3: chromatin binding level 3: transferase activity level 3: hydrolase activity level 4: protein kinase activity level 4: nucleotide binding level 5: kinase activity level 5: protein serine/threonine kinase activity level 5: metal ion binding level 6: ATP binding
GO Terms: Cellular Component	level 3: cytoplasm level 3: cytosol level 3: nucleolar chromatin level 4: mitochondrion level 4: kinetochore level 5: nucleus level 5: preribosome, small subunit precursor level 6: fungal-type vacuole
External source	Open in SGD