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Gene Ontology Information

Protein Name Mca1p
Description Ca2+-dependent cysteine protease; may cleave specific substrates during the stress response; regulates apoptosis upon H2O2 treatment; required for clearance of insoluble protein aggregates during normal growth; implicated in cell cycle dynamics and lifespan extension; undergoes autocatalytic processing; similar to mammalian metacaspases, but exists as a monomer due to an extra pair of anti-parallel beta-strands that block potential dimerization
GO Terms:
Biological Process		 level 5: proteolysis external link
level 5: apoptotic process external link
level 7: protein quality control for misfolded or incompletely synthesized proteins external link
GO Terms:
Molecular Function		 level 3: hydrolase activity external link
level 4: peptidase activity external link
level 5: cysteine-type peptidase activity external link
level 7: calcium-dependent cysteine-type endopeptidase activity external link
GO Terms:
Cellular Component		 level 3: cytoplasm external link
level 3: cytosol external link
level 5: nucleus external link
External source Open in SGD external link
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