S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ptp2p
Description	Phosphotyrosine-specific phosphatase; major role in osmolarity sensing through dephosphorylation of the Hog1p MAPK with a minor role by Ptp3p; inactivates and regulates Hog1p localization; major role in the cell wall integrity pathway through dephosphorylation of MAPK Slt2p with a minor role by Ptp3p; minor role with Msg5p in the pheromone adaptive response through dephosphorylation of MAPK Fus3p with major role by Ptp3p; co-regulates the calcium signaling pathway with Msg5p; nuclear localized
GO Terms: Biological Process	level 3: pheromone response MAPK cascade level 4: fungal-type cell wall organization or biogenesis level 5: regulation of sporulation level 6: maintenance of protein location in nucleus level 6: protein dephosphorylation level 6: dephosphorylation level 7: peptidyl-tyrosine dephosphorylation level 7: adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion level 9: negative regulation of cell wall integrity MAPK cascade
GO Terms: Molecular Function	level 3: hydrolase activity level 4: phosphoprotein phosphatase activity level 5: protein tyrosine phosphatase activity level 6: phosphatase activity
GO Terms: Cellular Component	level 3: cytoplasm level 5: nucleus
External source	Open in SGD