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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Protein Name
Hem4p
Description
Uroporphyrinogen III synthase; catalyzes the conversion of hydroxymethylbilane to uroporphyrinogen III, the fourth step in heme biosynthesis; deficiency in the human homolog can result in the disease congenital erythropoietic porphyria
GO Terms:
Biological Process
level 5:
heme biosynthetic process
level 6:
protoporphyrinogen IX biosynthetic process
level 6:
tetrapyrrole biosynthetic process
level 7:
uroporphyrinogen III biosynthetic process
level 7:
porphyrin-containing compound biosynthetic process
GO Terms:
Molecular Function
level 3:
lyase activity
level 6:
uroporphyrinogen-III synthase activity
GO Terms:
Cellular Component
level 1:
cellular_component
External source
Open in SGD