S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ldb19p
Description	Alpha-arrestin, Ub-ligase adaptor for Rsp5p; regulates starvation- and substrate-induced Ub-dependent endocytosis of select plasma membrane localized amino acid transporters, recruiting Rsp5p to its targets; role in basal internalization and turnover of Ste2p, mating and zygote formation; recruits Rsp5p to Ste2p via its 2 PPXY motifs; inhibited by Npr1p-mediated phosphorylation, affecting cytosol and plasma membrane translocation; localization regulated by Rsp5p-dependent ubiquitination
GO Terms: Biological Process	level 3: cell cycle level 5: protein transport level 6: ubiquitin-dependent endocytosis level 8: positive regulation of receptor internalization
GO Terms: Molecular Function	level 3: protein-macromolecule adaptor activity level 6: ubiquitin protein ligase binding
GO Terms: Cellular Component	level 3: cytosol level 3: cytoplasm level 4: Golgi apparatus level 4: plasma membrane level 6: clathrin-coated vesicle level 6: Golgi trans cisterna
External source	Open in SGD