S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Mip1p
Description	Mitochondrial DNA polymerase gamma; single subunit of mitochondrial DNA polymerase in yeast, in contrast to metazoan complex of catalytic and accessory subunits; polymorphic in yeast, petites occur more frequently in some lab strains; human ortholog POLG complements yeast mip1 mutant; mutations in human POLG associated with Alpers-Huttenlocher syndrome (AHS), progressive external ophthalmoplegia (PEO), parkinsonism, other mitochondrial diseases
GO Terms: Biological Process	level 6: DNA replication level 6: DNA biosynthetic process level 6: nucleic acid phosphodiester bond hydrolysis level 7: mitochondrial DNA replication level 7: mitochondrial DNA catabolic process level 7: mitochondrial genome maintenance
GO Terms: Molecular Function	level 3: transferase activity level 5: nucleotidyltransferase activity level 5: DNA binding level 6: DNA-directed DNA polymerase activity level 7: 3'-5' exonuclease activity
GO Terms: Cellular Component	level 4: mitochondrion level 4: gamma DNA polymerase complex
External source	Open in SGD