S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Nud1p
Description	Mitotic exit network (MEN) scaffold protein; core component of the SPB outer plaque that functions in astral microtubule organization via Spc72p; scaffold for recruitment of MEN components, such as Cdc15p, Tem1p and the Bfa1p-Bub2p checkpoint complex; phosphorylation by Cdc15p creates a Dbf2p-Mob1p phospho-docking site enabling Cdc15p-dependent complex activation and mitotic exit; acts through the MEN to specify Kar9p-mediated asymmetric SPB inheritance; homologous to mammalian centriolin
GO Terms: Biological Process	level 3: cell division level 3: meiotic cell cycle level 3: cell cycle level 4: meiotic chromosome segregation level 5: astral microtubule organization level 5: initial mitotic spindle pole body separation level 5: establishment of spindle localization level 9: positive regulation of exit from mitosis
GO Terms: Molecular Function	level 4: signaling adaptor activity level 4: dynein heavy chain binding level 6: alpha-tubulin binding
GO Terms: Cellular Component	level 3: cytoplasm level 4: spindle pole body level 4: outer plaque of mitotic spindle pole body level 4: nuclear envelope level 5: cytoskeleton level 5: nucleus
External source	Open in SGD