S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Chl1p
Description	Probable DNA helicase; involved in sister-chromatid cohesion and genome integrity and interstrand cross-link repair; interacts with ECO1 and CTF18; mutants are defective in silencing, rDNA recombination, aging and the heat shock response; FANCJ-like helicase family member; mutations in the human homolog, DDX11/ChLR1, cause Warsaw breakage syndrome
GO Terms: Biological Process	level 3: cell cycle level 4: establishment of sister chromatid cohesion level 4: nucleobase-containing compound metabolic process level 5: mitotic sister chromatid cohesion level 6: mitotic G1 DNA damage checkpoint signaling level 7: interstrand cross-link repair level 9: DNA duplex unwinding
GO Terms: Molecular Function	level 3: hydrolase activity level 3: helicase activity level 4: nucleotide binding level 4: nucleic acid binding level 4: DNA helicase activity level 5: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides level 5: DNA binding level 6: ATP binding
GO Terms: Cellular Component	level 3: chromatin level 5: nucleus
External source	Open in SGD