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Gene Ontology Information

Protein Name Atg21p
Description Phosphoinositide binding protein; required for vesicle formation in the cytoplasm-to-vacuole targeting (CVT) pathway, autophagy, micronucleophagy and mitophagy; binds to several phosphoinositides including: PtdIns(3,5)P2, PI3P and PI4P; involved in PI3P-dependent recruitment and organization of both the Atg12-Atg5-Atg16 complex and Atg8p at the pre-autophagosomal structure; necessary for oxidant-induced cell death; WD-40 repeat containing PROPPIN family member
GO Terms:
Biological Process
level 4: autophagy external link
level 4: cytoplasm to vacuole transport by the Cvt pathway external link
level 5: autophagy of nucleus external link
level 5: protein transport external link
level 5: macroautophagy external link
level 5: autophagy of mitochondrion external link
level 6: piecemeal microautophagy of the nucleus external link
level 6: protein lipidation external link
level 6: vesicle organization external link
level 6: protein localization to phagophore assembly site external link
GO Terms:
Molecular Function
level 5: phosphatidylinositol-3,5-bisphosphate binding external link
level 7: phosphatidylinositol-4-phosphate binding external link
level 7: phosphatidylinositol-3-phosphate binding external link
GO Terms:
Cellular Component
level 3: phagophore assembly site external link
level 3: extrinsic component of membrane external link
level 3: cytoplasm external link
level 3: cytosol external link
level 4: endosome external link
level 4: phagophore assembly site membrane external link
level 4: vacuole external link
level 7: fungal-type vacuole membrane external link
External source Open in SGD external link
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