S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Dbp1p
Description	ATP-dependent RNA helicase of the DEAD-box protein family; accelerates eIF4F-dependent assembly of 48S translation preinitiation complex (PIC), stimulating recruitment of mRNAs with long, structured 5'-UTRs; cooperates with DEAD-box RNA helicase and paralog Ded1p, stimulating PIC attachment and highly processive scanning by the 40S ribosomal subunit; protein abundance increases in response to DNA replication stress
GO Terms: Biological Process	level 4: translational initiation level 5: translation level 8: positive regulation of formation of translation preinitiation complex
GO Terms: Molecular Function	level 3: hydrolase activity level 3: ATP hydrolysis activity level 3: helicase activity level 4: RNA helicase activity level 4: DNA/RNA helicase activity level 4: nucleotide binding level 4: nucleic acid binding level 5: translation initiation factor activity level 5: RNA binding level 6: single-stranded RNA binding level 6: mRNA binding level 6: ATP binding
GO Terms: Cellular Component	level 3: cytoplasm level 5: nucleus
External source	Open in SGD