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Gene Ontology Information

Protein Name Ume1p
Description Component of both the Rpd3S and Rpd3L histone deacetylase complexes; negative regulator of meiosis; required for repression of a subset of meiotic genes during vegetative growth, binding of histone deacetylase Rpd3p required for activity, contains a NEE box and a WD repeat motif; homologous with Wtm1p; UME1 has a paralog, WTM2, that arose from the whole genome duplication
GO Terms:
Biological Process
level 3: meiotic cell cycle external link
level 5: chromatin organization external link
level 6: regulation of meiotic nuclear division external link
level 6: chromatin remodeling external link
level 7: histone deacetylation external link
level 7: regulation of DNA-templated transcription external link
level 9: positive regulation of transcription by RNA polymerase II external link
level 9: negative regulation of transcription by RNA polymerase I external link
GO Terms:
Molecular Function
level 4: transcription corepressor activity external link
level 4: histone binding external link
GO Terms:
Cellular Component
level 3: cytoplasm external link
level 4: Rpd3L-Expanded complex external link
level 5: Rpd3S/Clr6-CII complex external link
level 5: Rpd3L complex external link
level 5: nucleus external link
External source Open in SGD external link
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