Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Gene Ontology Information

Protein Name Tyw1p
Description Iron-sulfer protein required for synthesis of Wybutosine modified tRNA; Wybutosine is a modified guanosine found at the 3'-position adjacent to the anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions; induction by Yap5p in response to iron provides protection from high iron toxicity; overexpression results in increased cellular iron
GO Terms:
Biological Process		 level 6: wybutosine biosynthetic process external link
level 8: tRNA processing external link
GO Terms:
Molecular Function		 level 2: catalytic activity external link
level 3: lyase activity external link
level 4: iron-sulfur cluster binding external link
level 4: nucleotide binding external link
level 4: S-adenosyl-L-methionine binding external link
level 5: 4 iron, 4 sulfur cluster binding external link
level 5: FMN binding external link
level 5: metal ion binding external link
level 6: tRNA-4-demethylwyosine synthase activity external link
GO Terms:
Cellular Component		 level 4: endoplasmic reticulum external link
External source Open in SGD external link
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