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Modelling prediction
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[metab] Optimisation
manipulating gene expression
manipulating TF expression
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Protein Name
Fum1p
Description
Fumarase; converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial distribution determined by the N-terminal targeting sequence, protein conformation, and status of glyoxylate shunt; phosphorylated in mitochondria
GO Terms:
Biological Process
level 4:
tricarboxylic acid cycle
level 5:
cellular response to DNA damage stimulus
level 6:
DNA repair
level 8:
fumarate metabolic process
level 8:
malate metabolic process
GO Terms:
Molecular Function
level 2:
catalytic activity
level 3:
lyase activity
level 6:
fumarate hydratase activity
GO Terms:
Cellular Component
level 3:
cytoplasm
level 3:
cytosol
level 4:
tricarboxylic acid cycle enzyme complex
level 4:
mitochondrion
level 5:
nucleus
level 5:
mitochondrial matrix
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