S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Plc1p
Description	Phospholipase C; hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate the signaling molecules inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in regulating many cellular processes; Plc1p and inositol polyphosphates are required for acetyl-CoA homeostasis which regulates global histone acetylation
GO Terms: Biological Process	level 3: signal transduction level 4: signal transduction involved in filamentous growth level 4: intracellular signal transduction level 4: lipid metabolic process level 5: lipid catabolic process level 6: phospholipid catabolic process level 6: inositol phosphate biosynthetic process level 6: phosphatidylinositol-mediated signaling level 9: protein localization to kinetochore
GO Terms: Molecular Function	level 3: hydrolase activity level 5: metal ion binding level 6: phosphoric diester hydrolase activity level 6: calcium ion binding level 8: phosphatidylinositol phospholipase C activity
GO Terms: Cellular Component	level 4: chromosome, centromeric region level 4: kinetochore
External source	Open in SGD