S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rec8p
Description	Meiosis-specific component of the sister chromatid cohesion complex; alpha-kleisin family member that maintains cohesion between homologous chromosomes during meiosis I until chromosome arm-associated Rec8p is cleaved by Esp1p; cohesion between sister chromatid centromeres is maintained until metaphase of meiosis II when it is cleaved by Esp1; independent of the role in cohesion, Rec8p promotes allelic collisions and prevents nonspecific chromosome interactions; homolog of S. pombe Rec8p
GO Terms: Biological Process	level 3: meiotic cell cycle level 3: chromosome segregation level 4: sister chromatid cohesion level 4: reciprocal meiotic recombination level 5: meiotic DNA double-strand break formation level 5: meiotic sister chromatid cohesion level 5: monopolar spindle attachment to meiosis I kinetochore level 5: synaptonemal complex assembly level 5: positive regulation of cohesin unloading level 6: meiotic sister chromatid cohesion, centromeric level 6: meiotic sister chromatid cohesion involved in meiosis I level 7: double-strand break repair level 8: protein localization to chromosome, centromeric region
GO Terms: Molecular Function	level 3: chromatin binding
GO Terms: Cellular Component	level 4: chromosome, centromeric region level 4: cohesin complex level 5: nucleus level 5: chromosome level 5: condensed chromosome, centromeric region level 5: meiotic cohesin complex level 6: condensed nuclear chromosome
External source	Open in SGD