S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Mcm4p
Description	Essential helicase component of heterohexameric MCM2-7 complexes; MCM2-7 complexes bind pre-replication complexes on DNA and melt DNA prior to replication; forms an Mcm4p-6p-7p subcomplex; shows nuclear accumulation in G1; homolog of S. pombe Cdc21p
GO Terms: Biological Process	level 3: cell cycle level 4: nuclear DNA replication level 5: pre-replicative complex assembly involved in nuclear cell cycle DNA replication level 5: mitotic DNA replication initiation level 6: DNA replication initiation level 6: DNA replication level 7: DNA strand elongation involved in DNA replication level 8: DNA unwinding involved in DNA replication level 8: protein hexamerization level 9: double-strand break repair via break-induced replication level 9: DNA duplex unwinding
GO Terms: Molecular Function	level 3: helicase activity level 3: hydrolase activity level 4: DNA helicase activity level 4: nucleotide binding level 5: DNA binding level 5: 3'-5' DNA helicase activity level 5: four-way junction helicase activity level 5: single-stranded DNA helicase activity level 6: single-stranded DNA binding level 6: ATP binding level 7: zinc ion binding level 8: DNA replication origin binding
GO Terms: Cellular Component	level 3: MCM complex level 3: MCM core complex level 3: cytoplasm level 4: nuclear replication fork level 4: nuclear pre-replicative complex level 4: DNA replication preinitiation complex level 4: replication fork protection complex level 5: CMG complex level 5: nucleus
External source	Open in SGD