S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Fhl1p
Description	Regulator of ribosomal protein (RP) transcription; has forkhead associated domain that binds phosphorylated proteins; recruits coactivator Ifh1p or corepressor Crf1p to RP gene promoters; also has forkhead DNA-binding domain though in vitro DNA binding assays give inconsistent results; computational analyses suggest it binds DNA directly at highly active RP genes and indirectly through Rap1p motifs at others; suppresses RNA pol III and splicing factor prp4 mutants
GO Terms: Biological Process	level 7: regulation of DNA-templated transcription level 9: regulation of ribosomal protein gene transcription by RNA polymerase II level 10: positive regulation of ribosomal protein gene transcription by RNA polymerase II level 10: negative regulation of ribosomal protein gene transcription by RNA polymerase II
GO Terms: Molecular Function	level 3: DNA-binding transcription factor activity level 5: DNA binding level 6: transcription corepressor binding level 6: transcription coactivator binding level 6: sequence-specific DNA binding level 8: RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO Terms: Cellular Component	level 3: chromatin level 5: nucleus level 5: nucleolus
External source	Open in SGD