S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Isr1p
Description	Predicted protein kinase; negatively regulates the hexosamine biosynthetic pathway (HBP), which converts fructose-6-phosphate into UDP-N-acetylglucosamine, a precursor of chitin biosynthesis, GPI-anchor formation and glycosylation; interacts genetically with GFA1, encoding the first enzyme in the HBP; involved in Gfa1p phosphorylation (S332, T334); contains a Pho85p-regulated SCF-CDC4 phosphodegron; unstable, cell cycle regulated protein, peaking at G1/S
GO Terms: Biological Process	level 6: protein phosphorylation level 6: phosphorylation level 7: negative regulation of UDP-N-acetylglucosamine biosynthetic process level 7: peptidyl-serine phosphorylation level 7: peptidyl-threonine phosphorylation
GO Terms: Molecular Function	level 3: transferase activity level 4: protein kinase activity level 4: nucleotide binding level 5: protein serine/threonine kinase activity level 5: kinase activity level 6: ATP binding
GO Terms: Cellular Component	level 1: cellular_component
External source	Open in SGD