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Gene Ontology Information

Protein Name Pin3p
Description Negative regulator of actin nucleation-promoting factor activity; interacts with Las17p, a homolog of human Wiskott-Aldrich Syndrome protein (WASP), via an N-terminal SH3 domain, and along with LSB1 cooperatively inhibits the nucleation of actin filaments; short-lived protein whose levels increase in response to thermal stress; induces the formation of the [PIN+] and [RNQ+] prions when overproduced; PIN3 has a paralog, LSB1, that arose from the whole genome duplication
GO Terms:
Biological Process		 level 9: negative regulation of Arp2/3 complex-mediated actin nucleation external link
GO Terms:
Molecular Function		 level 1: molecular_function external link
GO Terms:
Cellular Component		 level 3: cytoplasm external link
level 4: actin cortical patch external link
level 5: nucleus external link
level 5: cytoskeleton external link
External source Open in SGD external link
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