Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
QDR3
Systematic Name
YBR043C
Alias
AQR2
Strain
S288c
Description
Multidrug transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; has a role in polyamine homeostasis; involved in spore wall asembly; sequence similarity to DTR1 and QDR1, and the triple mutant dtr1 qdr1 qdr3 exhibits reduced dityrosine fluorescence relative to the single mutants; expression is upregulated under polyamine stress; required for resistance to quinidine, barban, cisplatin, and bleomycin
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>QDR3 YBR043C
ATGCAAGCCCAAGGTTCACAATCGAATGTAGGGTCTTTGAGGAGTAATTGCTCTGACAAT
TCACTACCGAACAATCATGTTATGATGCACTGCGATGAAAGCAGCGGCAGCCCGCACAGC
GAGCACAACGATTATAGTTACGAAAAGACCAATCTGGAAAGTACGGCATCAAATAGTCGT
GAACACAGAGACAACCAGCTAAGTAGGTTGAAGAGTGAGGAATACGTTGTTCCAAAGAAT
CAACGTAGGGGACTATTGCCTCAACTCGCCATTATACCGGAGTTCAAGGATGCCAGAGAT
TATCCACCGATGATGAAAAAGATGATTGTCTTCTTGATTGCGTTTTCCTCCATGATGGGC
CCCATGGGCACATCTATCATTTTTCCAGCGATCAACTCAATCACAACAGAATTTAAAACA
TCAGTGATTATGGTAAACGTTTCAATTGGTGTGTACCTTTTAAGTCTTGGTGTTTTCCCA
TTGTGGTGGTCTTCTCTATCCGAGCTAGAGGGCAGAAGAACTACTTACATAACTTCATTT
GCATTATTGTTTGCATTTAATATCGGGTCTGCTCTAGCTCCTGATATCAACTCATTTATT
GCCTTGAGAATGCTCTGTGGGGCTGCTTCTGCCAGTGTTCAAAGTGTAGGTGCTGGAACA
GTGGCTGATTTATATATTAGCGAAGATAGAGGTAAAAATTTGAGTTATTACTATTTGGGT
CCACTACTGGCGCCGCTACTATCTCCAATTTTTGGATCTTTGTTAGTGAATCGCTGGCCC
TGGAGATCCACTCAATGGTTTATGGTTATTTTATCCGGATGTAATGTCATTCTTTTGACG
GTGTTACTACCTGAAACATTAAGAAAACAAGATTCTAAAGGCGCTATCGCTCAAATTTTG
GCTGAAAGACGTATTCAAGTAGACAATAACGAACGTGGAGAGATACAAGAAGATTATCAG
AGGGGAGAAGATGAGACAGATCGAATTGAAAACCAAGTTGCCACATTATCTACTGAGAAG
CATAACTACGTTGGAGAGGTAAGGGATCAAGACTCGCTAGATTTAGAAAGTCACTCTAGC
CCCAATACTTATGATGGTCGAGCTGGAGAAACCCAATTGCAACGGATTTATACAGAGGCG
AGTAGAAGTCTGTATGAATATCAGCTAGATGATAGCGGTATCGATGCAACAACAGCACAA
GTTACGAGAATAAGATCAACAGATCCAAAGTTAGCGAGATCGATTCGAGAAAATAGTCTG
AGAAAATTACAAACCAACCTGGAAGAGCAAGTCAAAAAAGTGCTATCCAGTAATGGAGGT
GAAATCGCTCCTAAACAGGTATCAGCGGTGAGGAAGGTCTGGGACACCTTTTTTGTTTAT
TTTATCAAGCCTTTAAAATCATTGCACTTCCTAGAATATCCACCCGTGGCACTTGCAATA
ACATTTTCCGCAATTTCCTTTTCCACAGTATACTTTGTTAATATGACAGTTGAATATAAA
TATTCAAGGCCTCCTTACAACTTTAAACCATTATACATTGGTCTACTGTATATTCCGAAT
TCTGTAACATACTTTTTCGCCTCAATTTACGGTGGACGTTGGGTGGACATGCTTTTAAAA
AGATACAAAGAGAAATATGGAATTCTTGCTCCTGAAGCTCGTATATCGTGGAATGTTGTT
ACATCTGTAATATCTTTCCCCATTGCGCTATTGATATTTGGCTGGTGCCTAGATAAAAAA
TGCCACTGGGTAACGCCACTAATTGGAACAGCCCTCTTTGGATATGCAGCTATGATGACA
ATTGGTGCTACCCTTTCCTATTTAGTCGATTCATTGCCGGGAAAGGGTGCCACCGGTGTT
GCTTTGAATAATTTAATAAGGCAAATCTTGGCTGCAACCGCAGTCTTTGTCACCACACCC
ATGTTAAACGGTATGGGAACTGGGTGGGCTTTCACAATGCTGGCCTTTATCGTCTTGGGT
GCTAGCAGTGTACTTATAATACTGAAAAAGCACGGTGATTACTGGAGAGAGAACTACGAT
TTACAAAAATTGTACGACAAAATTGATTAA
Promoter Sequence
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>QDR3 YBR043C
GCAGTATCGAATCCATAAAAGCGACCACAGGGGAGGCATTCTTATATAACTCCATTGATG
CTGAAGCGATTCCAAATAAAGTTCCGAAATCCTTCCTCCAAAATACGGTCACTTTAAGCA
TTGGTGGACATAACGAAATCGAAATCGACAGAAGAAGAAATGCAATAGATAATTGCTTAA
ATAACGTCCTATGTCATGGGCTGGCCAAAGGTTTCATCCCAGGTTACGGCATCTCCCTAC
TGAAGGCAATTCCAGGTTTGAATGAACTGAAAGCAAATGAACCCAATTTCATGACTAAGG
TAGGCATCAATGCTGTTTTATCAGCAGTTATTCTCCCATCAGAAGTGGCGTTTAAGAATG
CATATGGGTACAACTATTATGAGATCAATAGCCTGATAGCAGGCGCTATAAACGAAAAAT
CGTTTCCAATGGCCAAGTTTTCTCCAAATTCAGAACCGGTGAACACAGTAAAGGATGGAA
ACTTGGAGCCATGGAGCAAAATGGATTCTTGTTTAGCCGGTGTAGAAACGTTCATTGAAT
TACTTACAAGCTGTAATACAATTATCACATGTGTATACAAAAAGCCTGAACGGCACAAAG
CCTAGATAAAGCCCTTACATACTTTTAAATAGTCAGAATGAGTCATTGTAAATAGATATT
GCCACGGCGCTGCCTTTTATCACTTTTACCTCTTCGTAAATATCTATTATTCCTGCTCAA
TTTCTCATATGCGGCTTCGGAAAAACTCGGGTTTTTCCACGCCTCAGCAGTAACTCCATC
TACCTTTGGGGATTTGAACCATCTCATTCCAGTTTTGGATAACTGCGATTAGATTAAAAT
ATTAAAAGATTATCGATTAGATAAGATAGAAACCAACAAAATTTGTTGTAATAGCTGTGT
CCTTGTATCCTTAAAAGAAAACAGGGTTGAAGGCATATGTATTCACATCTTTCTAACTTG
TTAACGTCTATGCTAGGACCGAAGTCAGAAAGCGATAAAC
Chr coordinates
Chr II from 323945-321876