Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
FZO1
Systematic Name
YBR179C
Alias
mitofusin
Strain
S288c
Description
Mitofusin, protein involved in mitochondrial outer membrane fusion; role in mitochondrial genome maintenance; efficient tethering and degradation of Fzo1p requires an intact N-terminal GTPase domain; targeted for destruction by the ubiquitin ligase SCF-Mdm30p and the cytosolic ubiquitin-proteasome system; activity regulated by ubiquitylation at conserved lysine residues and by deubiquitylases Ubp2p and Ubp12p
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>FZO1 YBR179C
ATGTCTGAAGGAAAACAACAATTCAAAGACAGCAATAAACCGCACAAGGACTCCACAGAT
CAGGACGATGATGCCGCCACAATAGTACCACAAACTCTTACTTACTCACGCAACGAAGGT
CATTTTTTAGGCAGTAATTTCCATGGAGTAACTGATGACCGTACCACTTTGTTTGATGGT
GAAGAGGGGCGTAGGGAGGATGATTTGTTGCCCTCATTGCGTTCCTCCAACTCAAAAGCA
CACTTAATTTCTTCACAACTTAGCCAGTGGAATTATAACAACAATAGAGTACTTTTAAAA
AGATCTATATTAAAGACACAAGCTTTTATGGATCAACTTCAAGAAGAAAATAATATTCGC
CCGATTTTTATTGCTGCAAATGATGAACGGGAAAAATTACATGTTCTACAACTGAATATC
AAGCTAGATGGTCAGTACAATACCAAAGAAAAGAACGGTTTCAACATTGAGAAAAAAGCT
TTATCAAAATTATTTCACTCTCAGATCGTATCAGTGACAAATCATTTAAACGCTTTGAAA
AAAAGAGTGGATGACGTTTCATCTAAAGTATTCATCACAGGTGATGTAAATACTGGTAAA
TCAGCTCTTTGCAACTCTCTATTAAAGCAGCGTTTGCTACCTGAGGATCAGCTACCATGT
ACCAATGTATTTTCCGAAATACTAGAGGCTCGGGAAAATGACGGCATAGAGGAGGTTCAT
GCCATACCACTAAACATTGCTCCGACTCTCAAGGAAGCCATTGATATGTATTCAATACAA
AATCCCAAGACTTATGAAATACACACTTTGAAAGAACTTCCCGATTTGGTTCCCCAAAAC
GGAAAATATGCTTTACTGAAGATTTACATAAAGGACGATAAAAGGCCTGCCTCTACTAGT
CTATTAAGGAATGGTACTGTTGATATTTCATTAATTGACTCCCCTGGGTTGAACATGGAC
TCGTTACAAACCGCCGAAGTAATGTCCCGACAAGAAGAAATCGACTTAGTTATATTTGTT
GTCAATGCAGAGAACCAGCTAACACTATCTGCCAAGGAGTTTATTTCTTTAGCATCTCGT
GAGAAAAAATTAATGTTTTTTGTTGTGAAAAAATTTGACAAAATCAGGGACAAACAACGT
TGTAAGGAGTTGATCCTAAAGCAAATCCGTGACCTGTCCCCAGAAACATATAAACGTGCA
GCTGATTTTGTCCACTTTGTTTCCAAAAACGGAGATGAATTGCCACATTATCATAATGAA
AATGACAATGAAGATCATGGTGACCGAAAACCTGACGACGACCCATATTCTAGCAGCGAT
CCCGATCCGGATTTTGACAGTCTGGAAGATTCTCTACGCAATTTTGTTTTGAAGAAAAGA
TCACTTTCTAAATTGTTACCTGCCAAGACTTATCTATCGAAATTATTAAGCGATATAATA
ATGATCTCCAAATCTAATATGAAAATGTATAGTGAAGAAGAAATAAAAATTAACGAACAA
CTGGAAACATTGAGACCTGAAATTTTGAGCGCTAGAGCAAAGTGCAATGATTTAACAACT
TCCGTTGATCAAATGGCCGAGCAAACAATTACAATGACTTATAACAATACTAAAGAAGCA
CTTCTCAATGCGTTGGATGTTCCGCTACACGAATATCCGAAATATCAGGGCCTCGGTCAA
ATTTATGACTTCATATTTTCAACAGAAGCGTTCATAGCAAATCAGATTGATGAGTCAATA
GGATCAAGTGAATTATTTGCCAAGCAAAAGACAGATTTACTGGTAAAAAAAATTTATGAG
ATTGGAAAAAATGAACTTGGTGATGATTTCATGTGTGAACGTGTTTTCAGAAGCGAACTA
ATGTTTAGAAAAAGGAAGCATTTGATAGGAAAAAGGCTTAAAGTATCTTTGTCAATAACT
GATTTGTTTGCTCCAACTTGGAAAGGCTTTTTGTCTTACTTAAGCTGGCAGAAACCTGTC
ACAGCACCACTGCCGGATATAGAAGGACAAACTAACGAGGGTCAGATTGGCCTAATGAAG
TATTTGGGTTTGAAAAATTATCCTTTGACACAATATTGGTCAAGACCATCATTGCTCTTC
ACATCAAAAATTCCCACTCTAACGCTGTACTTTCTAGGAAGTACAAAGGTTGTGGGGAAC
ATTATATTAAACGGCATTAAATTATCGTCGTGGAGCTCACTCAAGAAGTTATCAGTTCCG
GTTATAGTGGTAGGTTCCTTGTTGGGACTTACGTATTTAATTCATGACCTCCCCCGTGCC
TTACCAATGAATCTTTCCATTAAATACAAAAGAAAGTTGCAAGAACTGGATTACATTCAT
CTTAACGCTCAAAGAACCTCAAATGAAGTACGTGATGTTTTGCGTGTACCTACACGTGAA
ATTCTAAGGTCGTGTGAAATAATTATGGATAAAAAACAAATCACTAAGAAAGAATTGGAA
AACAAAAAAGAAAGTAACTTGTTGTCAATCAAATTCTTCCAATCTCTATACGAAGGAACC
GTGGCTCAAAAATTGATGGTGGAAGAAATAAATTTAGACATCGATTAG
Promoter Sequence
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>FZO1 YBR179C
ATTGGGCCCAAAAATCCTATAAAAATGATAATTCCAAAAATGATTAGTCTTTGATCCTTG
GAAAAATAAGTATATGGAATATGTGCTTGAGTATCAGGAGAAGGGTCTCTTGACTGGGAG
TTCGATGACTTTACAGCAACTTCCTCTTCTTTTGTTTTTGCTTTCTGTGCTGACAATGAT
GGGGAAGAGTCAGGGTGCTCATGAAAGACATCATGATCTATATTGGCTCTCTTTTGGTTC
ACCTGATCCCAGCTTTCATTAATTACATCATCTCCTAGATCTTCTAGCGAATGAAATGTT
GAGCGGGTTGTTCCACTTTCTTGCGAATTAATTTGCAGACCCAAATTCTTTTTCTGAAAC
GGTTCGCTTCCCATTGCCTTAATTCTTTTCCCAGCTCTTGAAACTCTTTTTTGAAAAATT
ACCAACAACAACTTTTCTTACTACCATCCTTCTAGCCTTATCAATATTCTCATATATCTT
AAAATTGCAATTGTTGTTACAAAGGAGTTTGTGTCGTTTTTCACCAGGTGACAGAATGTC
TGGGTTGAAAGTATCAATGAAAAAAAAAAATGTAGAGAGATGCCAAAACAGTGGCCAACA
GGCAGCTTTGGCTACGGAAATGATTTGGAAACCTGCATAAGTATTTCTCCGCGAAATTGG
GAAGAGTGATATGGATAGTTGTGATCCACGGTATATAATTCCTTGTGATCCCTTATCTGG
CAAGATAGCTATAGTATTACTAATACGTGGCGCTAGTATAATAACTCGCGCAAAGACCGA
ACGGAGATTAATATTTAAAAGTTGGTGCGCAGTCCGGGTAAATACAGCTTTTCATGCTGA
AGAATATGGCCGGGCTAATATTAATTAAGACGGACGATGCATTATTGAAACAGGATAACG
CAGGTTACAGTAGCCCTTAATAAATAAAGCAAAGTACATCCGAACATAGCAACATTATCT
GATATCACGGATAGAGGCAAAACGGTAGGCTCATTTAACG
Chr coordinates
Chr II from 589114-586547