Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name PDI1
Systematic Name YCL043C
Alias MFP1, TRG1
Strain S288c
Description Protein disulfide isomerase; multifunctional oxidoreductase of the ER lumen, essential for disulfide bond formation in secretory and cell-surface proteins, processing of non-native disulfide bonds; Ero1p activator; complexes with exomannosidase, Mnl1p to facilitate the recognition of misfolded glycoproteins and the trimming of glycan Man8GlcNAc2 to Man7GlcNAc2 on substrates, thereby accelerating ERAD; PDI1 has a paralog, EUG1, that arose from the whole genome duplication
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>PDI1 YCL043C
CAGGTCGTCAGATGTGACGTTCTCATCGTCTAGCAAATCATCGGGAATCTTGGACTTCAT
TTGCTCCATGGAGAAAGTATGATCTCCATGCAAGTTAACAGAACATATACGGAAATTGGT
ACCACCCAGGTCGGCGGCTAGTAAAACACCGCGCTCCGTCCCGTTGGGTGACCCGGTGAC
GAACGCCGGAATCATAGGAAGACCTTTGTCCGAGGCCAATGTGTGGCCTTCCTTTGGTGG
AGCTAGACCTTTTTCCATTTGTTCGATGAAGTAAGCAGTTAATTCGTCCAGCTTCTCGGG
GGTAACCTCGAAATCGTCGCAGATCTGGTCCACGGCCTGGATGACCGCTCTCTCAGTGGC
TTTGTGTAAGTCGTCGAATGACATCTTGTGTATGATAGAGTTGTATTAGTGGTGGTGTTG
TGGTTTACGGAAGCTGAGTTGGGCACTGATGGGGGGGTTGGGGGTTCTGTTGATAGCGGA
TATTTATATGGGCGCGTTTTCATTAGTGCCCACCGTTTGAGCGTGGTGTGACACCACGCC
CAAGATAGGGGGCCCCCTGAAAGGGGTTGACCGTCCGTCGGCACACCACTTATAATGCGG
GGTGCAAGCGCCGCGTCTAAAATTTTTTTTTTTTCCATTTTTGTCGTTATTGTTATTTCC
CGTTTTTTGTTTTTTTTGATTTTTTCGGAGCGACAAACCTTTCGAAACACGTGTCCTGAA
AATTATCCTGGGCTGCACGTGATAATATGTTACCCTGTCGGGCGGCGCCTCTTTTTCCCT
TTTCTCTCACTAGTCTCTTTTTCCAATTTGCCACCGTGTAGCATTTTGTTGTGCTGTTAC
AACCACAACAAAACGAAAAACCCGTATGGACATACATATATATATATATATATATATATA
TTTTGTTACGCGTGCATTTTCTTGTTGCAAGCAGCATGTCTAATTGGTAATTTTAAAGCT
GCCAAGCTCTACATAAAGAAAAACATACATCTATCCCGTT
Chr coordinates Chr III from 50221-48653
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