Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
PDI1
Systematic Name
YCL043C
Alias
MFP1, TRG1
Strain
S288c
Description
Protein disulfide isomerase; multifunctional oxidoreductase of the ER lumen, essential for disulfide bond formation in secretory and cell-surface proteins, processing of non-native disulfide bonds; Ero1p activator; complexes with exomannosidase, Mnl1p to facilitate the recognition of misfolded glycoproteins and the trimming of glycan Man8GlcNAc2 to Man7GlcNAc2 on substrates, thereby accelerating ERAD; PDI1 has a paralog, EUG1, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>PDI1 YCL043C
ATGAAGTTTTCTGCTGGTGCCGTCCTGTCATGGTCCTCCCTGCTGCTCGCCTCCTCTGTT
TTCGCCCAACAAGAGGCTGTGGCCCCTGAAGACTCCGCTGTCGTTAAGTTGGCCACCGAC
TCCTTCAATGAGTACATTCAGTCGCACGACTTGGTGCTTGCGGAGTTTTTTGCTCCATGG
TGTGGCCACTGTAAGAACATGGCTCCTGAATACGTTAAAGCCGCCGAGACTTTAGTTGAG
AAAAACATTACCTTGGCCCAGATCGACTGTACTGAAAACCAGGATCTGTGTATGGAACAC
AACATTCCAGGGTTCCCAAGCTTGAAGATTTTCAAAAACAGCGATGTTAACAACTCGATC
GATTACGAGGGACCTAGAACTGCCGAGGCCATTGTCCAATTCATGATCAAGCAAAGCCAA
CCGGCTGTCGCCGTTGTTGCTGATCTACCAGCTTACCTTGCTAACGAGACTTTTGTCACT
CCAGTTATCGTCCAATCCGGTAAGATTGACGCCGACTTCAACGCCACCTTTTACTCCATG
GCCAACAAACACTTCAACGACTACGACTTTGTCTCCGCTGAAAACGCAGACGATGATTTC
AAGCTTTCTATTTACTTGCCCTCCGCCATGGACGAGCCTGTAGTATACAACGGTAAGAAA
GCCGATATCGCTGACGCTGATGTTTTTGAAAAATGGTTGCAAGTGGAAGCCTTGCCCTAC
TTTGGTGAAATCGACGGTTCCGTTTTCGCCCAATACGTCGAAAGCGGTTTGCCTTTGGGT
TACTTATTCTACAATGACGAGGAAGAATTGGAAGAATACAAGCCTCTCTTTACCGAGTTG
GCCAAAAAGAACAGAGGTCTAATGAACTTTGTTAGCATCGATGCCAGAAAATTCGGCAGA
CACGCCGGCAACTTGAACATGAAGGAACAATTCCCTCTATTTGCCATCCACGACATGACT
GAAGACTTGAAGTACGGTTTGCCTCAACTCTCTGAAGAGGCGTTTGACGAATTGAGCGAC
AAGATCGTGTTGGAGTCTAAGGCTATTGAATCTTTGGTTAAGGACTTCTTGAAAGGTGAT
GCCTCCCCAATCGTGAAGTCCCAAGAGATCTTCGAGAACCAAGATTCCTCTGTCTTCCAA
TTGGTCGGTAAGAACCATGACGAAATCGTCAACGACCCAAAGAAGGACGTTCTTGTTTTG
TACTATGCCCCATGGTGTGGTCACTGTAAGAGATTGGCCCCAACTTACCAAGAACTAGCT
GATACCTACGCCAACGCCACATCCGACGTTTTGATTGCTAAACTAGACCACACTGAAAAC
GATGTCAGAGGCGTCGTAATTGAAGGTTACCCAACAATCGTCTTATACCCAGGTGGTAAG
AAGTCCGAATCTGTTGTGTACCAAGGTTCAAGATCCTTGGACTCTTTATTCGACTTCATC
AAGGAAAACGGTCACTTCGACGTCGACGGTAAGGCCTTGTACGAAGAAGCCCAGGAAAAA
GCTGCTGAGGAAGCCGATGCTGACGCTGAATTGGCTGACGAAGAAGATGCCATTCACGAT
GAATTGTAA
Promoter Sequence
Download FASTA
>PDI1 YCL043C
CAGGTCGTCAGATGTGACGTTCTCATCGTCTAGCAAATCATCGGGAATCTTGGACTTCAT
TTGCTCCATGGAGAAAGTATGATCTCCATGCAAGTTAACAGAACATATACGGAAATTGGT
ACCACCCAGGTCGGCGGCTAGTAAAACACCGCGCTCCGTCCCGTTGGGTGACCCGGTGAC
GAACGCCGGAATCATAGGAAGACCTTTGTCCGAGGCCAATGTGTGGCCTTCCTTTGGTGG
AGCTAGACCTTTTTCCATTTGTTCGATGAAGTAAGCAGTTAATTCGTCCAGCTTCTCGGG
GGTAACCTCGAAATCGTCGCAGATCTGGTCCACGGCCTGGATGACCGCTCTCTCAGTGGC
TTTGTGTAAGTCGTCGAATGACATCTTGTGTATGATAGAGTTGTATTAGTGGTGGTGTTG
TGGTTTACGGAAGCTGAGTTGGGCACTGATGGGGGGGTTGGGGGTTCTGTTGATAGCGGA
TATTTATATGGGCGCGTTTTCATTAGTGCCCACCGTTTGAGCGTGGTGTGACACCACGCC
CAAGATAGGGGGCCCCCTGAAAGGGGTTGACCGTCCGTCGGCACACCACTTATAATGCGG
GGTGCAAGCGCCGCGTCTAAAATTTTTTTTTTTTCCATTTTTGTCGTTATTGTTATTTCC
CGTTTTTTGTTTTTTTTGATTTTTTCGGAGCGACAAACCTTTCGAAACACGTGTCCTGAA
AATTATCCTGGGCTGCACGTGATAATATGTTACCCTGTCGGGCGGCGCCTCTTTTTCCCT
TTTCTCTCACTAGTCTCTTTTTCCAATTTGCCACCGTGTAGCATTTTGTTGTGCTGTTAC
AACCACAACAAAACGAAAAACCCGTATGGACATACATATATATATATATATATATATATA
TTTTGTTACGCGTGCATTTTCTTGTTGCAAGCAGCATGTCTAATTGGTAATTTTAAAGCT
GCCAAGCTCTACATAAAGAAAAACATACATCTATCCCGTT
Chr coordinates
Chr III from 50221-48653