S.cerevisiae - Yeastract

Locus Information

Standard Name	SLX5
Systematic Name	YDL013W
Alias	HEX3, ULS2
Strain	S288c
Description	Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex; role in Ub-mediated degradation of histone variant Cse4p preventing mislocalization to euchromatin; role in proteolysis of spindle positioning protein Kar9p, and DNA repair proteins Rad52p and Rad57p; forms SUMO-dependent nuclear foci, including DNA repair centers; contains a RING domain and two SIM motifs; associates with the centromere; required for maintenance of genome integrity like human ortholog RNF4
External sources	Open in SGD Open in KEGG

Gene Sequence Download FASTA View Seq	Sequence hidden
Promoter Sequence Download FASTA	>SLX5 YDL013W GTATGGTTGACTGTGTCTTCGCAGATGTTGCCCAGCCTGATCAAGCTCGTATTATTGCAT TGAACTCTCATATGTTCTTGAAGGACCAAGGTGGTGTTGTTATCTCCATTAAGGCTAACT GTATTGATTCTACTGTAGACGCGGAAACCGTTTTTGCTAGAGAAGTTCAAAAGTTACGTG AGGAACGTATTAAGCCATTAGAACAATTGACTTTAGAGCCATATGAAAGAGACCATTGTA TCGTCGTTGGTAGATACATGAGAAGCGGTTTGAAGAAATAAGTTGAATAAAGGAAATTAG TCAAAAGTTTCTGGTAGCTTGCTCAATTATTAGCAGAATAATTGTTTCGTTTATATATAT TTCCCCCATTCAGTTTCACTTCCTATTTGAAGTTTTTGTAACCCTCGACTTTGTAAAATA GATATTACTAAATTCTTTTAGAGAACAAAAGTATTGTACGTATTCGCCATATAAAAAAAA AAGAGTATATGTGGTGACTTTTTGGTCATTAATTGTTAAGAGCAAGCAAGTAGAAATCAT AATCATATTTCGAGTTTTTTAAAGGTAGGAACAATATCGATAAGCTGTTCTCCAGTCTCG ACACTGTTTGATGACCATATATCATTAATTCTTGTAACACTACATCATAGATTTCTCTTT ATCCTTGGATTGAATCTGAAAAAATTTTGATAGAGTCTTTTGTTCAAAGTGTCACTTCTT CATCTGTCACTCTTACGTATTTTTTTTTTTTTGGCTTTGCCCATAAGAAACATCACTGTA TACGCAAGGTCGCAATATTTACTATTTAACATGGATGAGAGGCAGTGTGCGACCAAAACG AAGACTTAATCATTAAGAAGAGCGTGTGTTGCGTTGATTGGTAATAACCAAGTCGAAATT TGCACTAGGAGCTTCAGTCTAGGAGTGAACTTTTGAAAAGATTTCAGTCCAAAAATTATT ATTTGGAACGCGGAGCTCCTCTAATAGTCGAAATAATAGA
Chr coordinates	Chr IV from 429067-430926