Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name NPC2
Systematic Name YDL046W
Strain S288c
Description Sterol transport protein and functional homolog of human NPC2/He1; acts with Ncr1p in sterol trafficking; human NPC2 is a cholesterol-binding protein whose deficiency causes Niemann-Pick type C2 disease involving retention of cholesterol in lysosomes; yeast NPC2 can complement mutations in human NPC2
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Gene Sequence
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Promoter Sequence
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>NPC2 YDL046W
ACGGTAAGATCTTATGTGTCCATGGAGGGTTATCTCCCGAGATTAGAATGCTCGATCAAA
TCAGAGTCTTGTCAAGAGCTCAAGAAGTGCCACACGAGGGTGGGTTCTCGGACCTGCTTT
GGTCAGACCCTGACAATGTAGAGGCTTGGCAAGTTTCCCCTCGTGGTGCAGGATGGCTCT
TTGGCAGTAAAGTTGCTAGAGAGTTTAACCACGTTAATGGACTGAACCTTATTGCCCGGG
CTCACCAACTGGTTATGGAGGGGTTCAAGTACCATTTTCCTGAAAAGGACGTTGTAACCG
TGTGGTCCGCGCCAAATTACTGTTATAGATGTGGTAATGTCGCGAGTGTAATGAAGGTCG
ATGAGGATCTGGAACCTACTTTCAAAATTTTCTCGGCTGTTCCCGATGACTACATAAGAG
AATCCACGGCAAACCATAATAATCAAAGAGCCGGCTATTTCTTATAACACGACGGCATGC
CCTCCCTAACTCGACGAATAAAAATAATTTTCACAATAAAAAAAAGACTACAAAAATCAG
AAACTTTTTCATTACGCCATTTGCTACGATACGATACACAACAAGCACATTCTAAGAGCA
TTCCATTTACTATGGTCAAAATGACCAAATAAAAAATTAAAAAAAAAAAGAAGGAATGAG
AACTAGTAACTACATATTCAACAATTGCAGTTTTCTTTTCCTTTTTGTCCTTGTCCTTTC
TTTCCTATTTATATATATATATATATATATATATAATACTACTATGTTATATTACATTAT
ATTATTATCACAATAATTATTACGTTCATCGTGCCGAAACGTCACCTCCCACGGTTTGGA
TCTATTGAAAGAGGGTGGAATCCCTGATAATAAAAAAACTTTAATCAACACTCGGGAGGG
GAAATATAAAAGACTGGCGCTACTTAAAGAGCTGATTCGCCAAGGCAGAAAAGCATAACC
ATATTAAATCTTCTCCTTCAAAGCTAGCACGCCTTCCAAA
Chr coordinates Chr IV from 371240-371761
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